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A new efficient route to imidazo[4,5‐ c ]pyrazol‐5‐ones
Author(s) -
Vicentini Chiara B.,
Veronese Augusto C.,
Manfrini Maurizio
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340246
Subject(s) - chemistry , combinatorial chemistry , stereochemistry , amino acid , biochemistry
The synthesis of imidazo[4,5‐ c ]pyrazol‐5‐ones ( 6 ) is reported. 5‐Amino‐4‐ethoxycarbonylaminopyra‐zoles 3a‐g when heated at 200° for 2 hours afford 6a‐g. In a similar manner imidazo[4,5‐ c ]pyrazol‐5‐one ( 6a ) is readily obtained from 4‐amino‐5‐ethoxycarbonylaminopyrazole ( 5a ).