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Tetracyclic systems: Synthesis of isoindolo[1,2‐ b ]thieno‐[2,3(3,2 or 3,4)‐ e ][1,3]thiazocines and Isoindolo[2,1‐ a ]thieno‐[2,3(3,2 or 3,4)‐ f ][1,4] and [1,5]diazocines
Author(s) -
Pigeon Pascal,
Decroix Bernard
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340203
Subject(s) - chemistry , beckmann rearrangement , thioglycolic acid , stereochemistry , medicinal chemistry , organic chemistry , oxime
Cyclization of thioglycolic acids derivatives 3a‐d gave isoindolo[1,2‐ b ]thieno[2,3(3,2 or 3,4)‐ e ][1,3]‐thiazocines 4a‐d . Isoindolo[2,1‐ a ]thieno[2,3(3,2 or 3,4)‐ f ][1,4] or [1,5]diazocines 10b or 11a‐c were synthesized from Beckmann or Schmidt rearrangement of the ketones 7a‐c .