Premium
1,3‐Dipolar cycloaddition reactions of cyclooctyne with pyridinium dicynomethylides
Author(s) -
Matsumoto Kiyoshi,
Ohta Ryuji,
Uchida Takane,
Nishioka Hiroyasu,
Yoshida Maki,
Kakehi Akikazu
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340130
Subject(s) - pyridinium , chemistry , cycloaddition , 1,3 dipolar cycloaddition , dipole , computational chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Cyclooctyne smoothly underwent 1,3‐dipolar cycloaddition with pyridinium dicyanomethylides to afford the corresponding indolizines (8‐cyario‐7‐azatricyclo[7.6.0.0 2,7 ]pentadeca‐1,3,5,8‐tetraenes) in excellent yields.