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Synthesis of new dihydrooxathiino[2,3‐ b ]quinoline
Author(s) -
Hahn HohGyu,
Chang Kee Hyuk,
Lee Wha Suk,
Yoo Ji Uk
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330681
Subject(s) - chemistry , potassium hydroxide , sulfuric acid , quinoline , condensation , ethanol , aqueous solution , potassium , organic chemistry , yield (engineering) , aqueous medium , nuclear chemistry , physics , materials science , metallurgy , thermodynamics
A synthesis of new dihydrooxathiinoquinoline 4 is described. The key compound 6 was prepared by known methods from acetoacetanilide 1 . A condensation of β‐chlorosulfide 6 in 75% aqueous sulfuric acid gave quinolone 5 . Conversion of 5 to 4 was achieved by treatment with potassium hydroxide in ethanol solution.
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