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A new synthesis of aryl substituted quinazolin‐4(1 H )‐ones
Author(s) -
Roth Gary A.,
Tai Jimmy J.
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330680
Subject(s) - chemistry , formic acid , yield (engineering) , aryl , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry , stereochemistry , materials science , metallurgy , alkyl
Treatment of a variety of substituted 2‐aminobenzonitriles with formic acid under strong acid catalysis provides the corresponding quinazolin‐4(1 H )‐ones in good yield. A potential reaction pathway is described.