Premium
A new synthesis of aryl substituted quinazolin‐4(1 H )‐ones
Author(s) -
Roth Gary A.,
Tai Jimmy J.
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330680
Subject(s) - chemistry , formic acid , yield (engineering) , aryl , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry , stereochemistry , materials science , metallurgy , alkyl
Treatment of a variety of substituted 2‐aminobenzonitriles with formic acid under strong acid catalysis provides the corresponding quinazolin‐4(1 H )‐ones in good yield. A potential reaction pathway is described.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom