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A new synthetic route to 7 H ‐imidazo[1,2‐ b ][1,2,4]triazoles
Author(s) -
Lee KeeJung,
Song DongHyuk,
Kim DongJin,
Park SangWoo
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330653
Subject(s) - chemistry , triethylamine , carbodiimide , benzil , triphenylphosphine , carbon tetrachloride , isocyanide , medicinal chemistry , organic chemistry , stereochemistry , catalysis
The reaction of benzil 1‐ureidoethylidenehydrazones 8 with a mixture of triphenylphosphine, carbon tetrachloride, and triethylamine provides a general route to 7 H ‐imidazo[1,2‐ b ][1,2,4]triazoles 18 via the thermal reaction of the expected ketoazine carbodiimide intermediates 13 , and the structure of 18 was confirmed by X‐ray crystallographic analysis.