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Pyirolothieno[1,4]diazepines. Part IV . First synthesis of pyrrolo‐[1,2‐ a ]thieno[2,3‐ f ][1,4]diazepine Derivatives
Author(s) -
Boulouard Michel,
Dallemagne Patrick,
Alsaïdi Abdellah,
Rault Sylvain
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330633
Subject(s) - chemistry , diazepine , nucleophile , medicinal chemistry , d 1 , stereochemistry , combinatorial chemistry , ring (chemistry) , organic chemistry , catalysis , receptor , biochemistry
Treatment of 3‐(2‐formyl‐1 H ‐pyrrol‐1‐yl)‐2‐thiophenecarboxamide by various nucleophiles like methyl ketones, amines, alcohols, thiols or acetates led to new 5,6‐dihydro‐4 H ‐pyrrolo[1,2‐ a ]thieno‐[2,3‐ f ][1,4]diazepines.