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Synthesis and reactivity of 2,3‐dihydro‐1 H ‐pyrrolo[1,2‐ a ]indole derivatives, analogs of the FR900482 and mitomycin C active intermediates
Author(s) -
Zhang Weihong,
Locurcio Michael,
Lin ChuanChuan,
Jimenez Leslie S.
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330617
Subject(s) - chemistry , indole test , nucleophile , reactivity (psychology) , mitomycin c , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , medicine , alternative medicine , surgery , pathology
A series of 2,3‐dihydro‐1 H ‐pyrrolo[1,2‐ a ]indoles were prepared as analogs of the active intermediates of the natural products, mitomycin C and FR900482, and their reactions with various nucleophiles were studied.