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3‐(2,5‐Dioxopyrrolidin‐1‐yl), 3‐(2,6‐dioxopiperidin‐1‐yl), and 3‐(1,3‐dioxoisoindolin‐2‐yl)rhodanines. a novel type of rhodanine derivatives
Author(s) -
Hanefeld Wolfgang,
Schlitzer Martin,
Debski Norbert,
Euler Helmut
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330423
Subject(s) - rhodanine , chemistry , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
3‐Aminorhodanine 2 was reacted with cyclic anhydrides yielding 3‐(2,5‐dioxopyrrolidin‐1‐yl), 3‐(2,6‐dioxopiperidin‐1‐yl), and 3‐(1,3‐dioxoisoindolin‐2‐yl)rhodanine 6‐8 , which in turn were condensated in 5 position with several aldehydes yielding the new rhodanine derivatives 9‐11 .
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