Premium
Mechanistic studies in the reaction of 4‐phenyl‐1,2,4‐triazoline‐3,5‐dione with 2,5‐dimethyl‐2,4‐hexadiene
Author(s) -
Vassilikogiannakis Georgios,
Stratakis Manolis,
Karabatsos Gerasimos J.,
Orfanopoulos Michael
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330374
Subject(s) - chemistry , imide , methanol , medicinal chemistry , adduct , kinetic isotope effect , organic chemistry , deuterium , physics , quantum mechanics
Secondary isotope effect measurements of methanol adducts from the reaction of 4‐phenyl‐1,2,4‐triazoline‐3,5‐dione with 2,5‐dimethyl‐2,4‐hexadiene, support the formation of an aziridinium imide intermediate rather than an open dipolar intermediate in the rate determining step.