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[1]Benzothienoindolizidinones and [1]benzothienoquinolizidinones: Synthesis and schmidt rearrangement into [1,3]diazepines derivatives
Author(s) -
Daïcb Adam,
Decroix Bernard
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330354
Subject(s) - chemistry , benzothiophene , schmidt reaction , cope rearrangement , medicinal chemistry , stereochemistry , organic chemistry , thiophene
[1]Benzothienoindolizidinones 5ac,ae,bc and [1]Benzothienoquinolizidinone 5ad were synthesized from 2(3)‐bromethyl[1]benzothiophene and methyl prolinate, methyl oxoprolinate and ethyl pipecolinate. The Schmidt rearrangement of ketones 5 led exclusively to the [1,3]diazepines derivatives 6 .