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The synthesis and determination of acidic ionization constants of certain 5‐substituted 2‐aminopyrrolo[2,3‐ d ]pyrimidin‐4‐ones and methylated analogs
Author(s) -
Hoops Geoffrey C.,
Park Julie,
Garcia George A.,
Townsend Leroy B.
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330341
Subject(s) - chemistry , ionization , computational chemistry , medicinal chemistry , organic chemistry , ion
The acidic ionization constants were determined for a series of 5‐substituted 2‐aminopyrrolo[2,3‐ d ]‐pyrimidin‐4‐ones and N ‐3‐ and N ‐7‐methylated analogs thereof. The syntheses of the methylated analogs are also described.