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5‐(α‐Fluorovinyl)tryptamines and 5‐(α‐Fluorovinyl)‐3‐( N ‐methyl‐1′,2′,5′,6′,‐tetrahydropyridin‐3′‐ and ‐4′‐yl)indoles—5‐(α‐Fluorovinyl)tryptamines
Author(s) -
Gharat Laxmikant A.,
Martin Arnold R.
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330134
Subject(s) - tryptamines , chemistry , organic chemistry , stereochemistry , tryptamine , biochemistry
5‐(α‐Fluorovinyl)tryptamines 4a, 4b and 5‐(α‐fluorovinyl)‐3‐( N ‐methyl‐1′,2′,5′,6′‐tetrahydropyridin‐3′‐ and ‐4′‐yl) indoles 5a, 5b were synthesized using 5‐(α‐fluorovinyl)indole ( 7 ). The target compounds are bioisosteres of 5‐carboxyamido substituted tryptamines and their tetrahydropyridyl analogs.
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