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New access to 4‐phenyl‐6 H ‐pyrrolo[1,2‐ a ]thieno[3,2‐ f ]‐[1,4]diazepines
Author(s) -
Foloppe MariePaule,
Sonnet Pascal,
Bureau Isabelle,
Rault Sylvain,
Robba Max
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330113
Subject(s) - chemistry , paraformaldehyde , diazepine , medicinal chemistry , ethanol , oxide , combinatorial chemistry , stereochemistry , organic chemistry , ring (chemistry)
Pyrrolo[1,2‐ a ]thieno[3,2‐ f ][1,4]diazepines were obtained in an original one step synthesis by treatment of imines 1 with paraformaldehyde in refluxing ethanol. The intermediate Mannich bases were also converted into the thienooxadiazocines 12 and the diazepine N ‐oxide 13 .
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