Premium
Polycyclic N ‐heterocyclic compounds. 48 . syntheses of furo[2,3‐ h ]‐[1,6]naphthyridine and imidazo(or pyrimido)[2,1‐ f ]‐[1,6]naphthyridines with rearrangement
Author(s) -
Sasaki Kenji,
Rouf Abu Shara Shamsur,
Hirota Takashi
Publication year - 1996
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570330109
Subject(s) - chemistry , stereochemistry , medicinal chemistry
The formation of a novel ring system, furo[2,3‐ h ][1,6]naphthyridine via the Smiles rearrangement and intramolecular cyclization is described. Cyclization of 5‐(ω‐hydroxyalkylamino)‐8‐methyl‐1,2‐dihydrofuro[2,3‐ h ][1,6]naphthyridines provided novel spiro compound with rearrangement.