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Thiazolo[4,3‐c][1,4]benzodiazepines. I. Synthesis of amidine derivatives
Author(s) -
Gillard AlainClaude,
Rault Sylvain,
Boulouard Michel,
Robba Max
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320613
Subject(s) - chemistry , amidine , benzodiazepine , reactivity (psychology) , benzazepines , lactam , medicinal chemistry , stereochemistry , medicine , biochemistry , alternative medicine , receptor , pathology
Reactivity of 1,2,3,10,11,11a‐hexahydro‐5 H ‐thiazolo[4,3‐ c ][1,4]benzodiazepin‐5‐one‐11‐thione and 1,2,3,10,11,11a‐hexahydro‐5 H ‐thiazolo[4,3‐ c ][1,4]benzodiazepine‐5,11‐dithione was evaluated against various amines. The synthetic pathways involved in these reactions which led to new thiazolo[4,3‐ c ]‐[1,4]benzodiazepine amidines are described.

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