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A novel synthesis of 5‐acylaminooxazoles
Author(s) -
Katritzky Alan R.,
Wu Hong,
Xie Linghong
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320544
Subject(s) - chemistry , sodium hydride , intramolecular force , condensation , diol , hydride , medicinal chemistry , primary (astronomy) , sodium , organic chemistry , combinatorial chemistry , hydrogen , physics , astronomy , thermodynamics
1,2‐Diacylamino‐1,2‐di(benzotriazol‐1‐yl)ethanes 2 , easily prepared from the condensation of 1,2‐di(benzotriazol‐1‐yl)ethane‐1,2‐diol (1) and primary amides, were converted to 5‐acylaminooxazoles in good to moderate yields via intramolecular cyclization upon treatment with sodium hydride.