Premium
A novel synthesis of 5‐acylaminooxazoles
Author(s) -
Katritzky Alan R.,
Wu Hong,
Xie Linghong
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320544
Subject(s) - chemistry , sodium hydride , intramolecular force , condensation , diol , hydride , medicinal chemistry , primary (astronomy) , sodium , organic chemistry , combinatorial chemistry , hydrogen , physics , astronomy , thermodynamics
1,2‐Diacylamino‐1,2‐di(benzotriazol‐1‐yl)ethanes 2 , easily prepared from the condensation of 1,2‐di(benzotriazol‐1‐yl)ethane‐1,2‐diol (1) and primary amides, were converted to 5‐acylaminooxazoles in good to moderate yields via intramolecular cyclization upon treatment with sodium hydride.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom