Premium
The synthesis of 5‐arylpyrrolo[3,2‐ b ]pyridines and 7‐arylpyrrolo[3,2‐ b ]pyridines: Addition of 3‐aminopyrroles to aryl enaminones
Author(s) -
Birnberg Gary H.,
Fanshawe William J.,
Francisco Gerardo D.,
Epstein Joseph W.
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320433
Subject(s) - chemistry , aryl , pyridine , sequence (biology) , product (mathematics) , stereochemistry , medicinal chemistry , organic chemistry , alkyl , biochemistry , geometry , mathematics
A series of 5‐arylpyrrolo[3,2‐ b ]pyridines 1 was synthesized by addition of 3‐aminopyrroles to aryl enaminones. One example of a 7‐arylpyrrolo[3,2‐ b ]pyridine 2 was obtained as a minor product along with the 5‐aryl isomer, by a modification of the reaction sequence.