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Enzymatic resolution of trans ‐2,3‐dihydro‐3‐hydroxy‐2‐phenyl‐4 H ‐1‐benzopyran‐4‐one ( trans ‐flavanon‐3‐ol) by lipase
Author(s) -
Izumi Taeko,
Murakami Satoshi
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320404
Subject(s) - chemistry , lipase , benzopyran , resolution (logic) , enzyme , stereochemistry , organic chemistry , artificial intelligence , computer science
trans ‐2,3‐Dihydro‐3‐hydroxy‐2‐phenyl‐4 H ‐l‐benzopyran‐4‐one ( trans ‐flavanon‐3‐ol) was resolved to acetate of (2 S ,3 S )‐(‐)‐ trans ‐flavanon‐3‐ol and (2 R ,3 R )‐(‐)‐ trans ‐flavanon‐3‐ol by an enzymatic transesterification with vinyl acetate in the presence of Pseudomonas cepacia lipase.