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Synthesis of 2‐aryl‐3‐trifluoromethylsulfonylpyrroles
Author(s) -
Barnes Keith D.,
Ward Randall
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320333
Subject(s) - chemistry , enamine , aryl , combinatorial chemistry , key (lock) , organic chemistry , catalysis , alkyl , ecology , biology
A general method for the preparation of 2‐aryl‐3‐trifluoromethylsulfonylpyrroles 2 has been developed. Procedures for the construction of the key enamine intermediates 9 and their cyclizations to pyrroles are reported.