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Hydrolysis of 4‐cyano‐1‐ethoxypyrimido[1,6‐ a ]benzimidazole: Formation of a ynaminonitrile and benzimidazolidines
Author(s) -
Zama Yoshimi,
Okamoto Yoshibisa,
Takagi Kaname,
Kurasawa Yoshihisa,
Takada Atsushi
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320329
Subject(s) - chemistry , benzimidazole , hydrolysis , organic chemistry , medicinal chemistry , stereochemistry
The title compound 4 was hydrolyzed to a new type of ynaminonitrile 5 and benzimidazolidines 7 and 9 under acidic or basic conditions. Reaction mechanisms were proposed.