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Regioselective synthesis of 6‐alkylated lumazine derivatives
Author(s) -
Igarashi Mamoru,
Tada Masaru
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320320
Subject(s) - chemistry , alkylation , enamine , regioselectivity , cycloaddition , deamination , decarboxylation , organic chemistry , catalysis , enzyme
The regiospecific synthesis of alkylated lumazines is achieved by hetero Diels‐Alder addition between an oxadiazinone 2 and enamine. The reactions proceed stepwise by cycloaddition, decarboxylation and deamination to produce the 6‐alkylated lumazines.