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Anodic cyanation of 1‐methylpyrazole
Author(s) -
Yoshida Kunihisa,
ToyoOka Yoshimasa,
Takeda Kazusada
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320255
Subject(s) - chemistry , cyanation , anode , medicinal chemistry , organic chemistry , electrode , catalysis
The electrooxidation of 1‐methylpyrazole in methanol containing sodium cyanide produced 1‐methyl‐pyrazole‐4‐carbonitrile 2 and −5‐carbonitrile 3 in yields of 23 and 8%, respectively (2e‐oxidation products), together with 4‐methoxy‐1‐methylpyrazole‐5‐carbonitrile 4 (4e‐oxidation product, 4%).