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Synthesis of novel 1‐alkyl or 1‐aryl‐2‐(4‐substituted‐1‐piperazinyl)‐1‐ H ‐benzothieno[2,3‐ d ]imidazoles
Author(s) -
Guerrera F.,
Salerno L.,
Sarvà M. C.,
Siracusa M. A.
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320237
Subject(s) - chemistry , aryl , alkyl , thiophene , nitro , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry
Abstract The synthesis of novel 1‐alkyl or 1‐aryl‐2‐(4‐substituted‐1‐piperazinyl)‐1‐ H ‐benzothieno[2,3‐ d ]imidazoles 7e‐x starting from 2‐nitro‐3‐bromobenzo[ b ]thiophene is described. These compounds were prepared as potential H 1 ‐antihistaminic agents.