Premium
Preparation of trifluoromethylated pyrazoles and 1,4‐thiazine 1,1‐dioxides from trifluoromethylated sulfone derivatives
Author(s) -
Takahashi Masahiko,
Chigira Keiko
Publication year - 1995
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570320134
Subject(s) - chemistry , thiazine , trifluoromethyl , sulfone , sulfonyl , organic chemistry , medicinal chemistry , alkyl
Trifluoromethylated sulfones, 3‐amino‐2‐arylsulfonyl‐4,4,4‐trifluoro‐3‐hydroxybutanenitrile ( 3 ) and 3‐(aroylmethyl)sulfonyl‐1,1,1‐trifluoropropane‐2,2,‐diols 12 , were prepared and cyclized to 4‐arylsulfonyl‐5‐trifluoromethyl‐3‐hydrazinopyrazoles 9 and 5‐arylsulfonyl‐3‐trifluoromethyl‐3‐hydroxy‐2,3‐dihydro‐4 H ‐1,4‐thiazine 1,1‐dioxides 13 , respectively.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom