Synthesis of 3‐[[(2‐benzimidazolyl)thio]methyl]‐1‐methyl‐1,8‐dihydrocycloheptapyrazol‐8‐ones | Zendy

Kugishima Hideki | Zendy; Horie Takahisa | Zendy; Imafuku Kimiaki | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of 3‐[[(2‐benzimidazolyl)thio]methyl]‐1‐methyl‐1,8‐dihydrocycloheptapyrazol‐8‐ones

Author(s) -

Kugishima Hideki,

Horie Takahisa,

Imafuku Kimiaki

Publication year - 1994

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570310647

Subject(s) - chemistry , thio , tropolone , methylhydrazine , medicinal chemistry , stereochemistry , organic chemistry , phenylhydrazine

3‐(Bromoacetyl)tropolone was reacted with five 2‐mercaptobenzimidazoles to give 3‐[[(2‐benzimidazolyl)thio]acetyl]tropolones. These products were heated with methylhydrazine to afford 3‐[[(2‐benzimidazolyl)thio]methyl]‐1‐methyl‐1,8‐dihydrocycloheptapyrazol‐8‐ones. In these reactions, 1‐methyl‐3‐[(1‐methylhydrazino)methyl]‐1,8‐dihydrocycloheptapyrazol‐8‐one was isolated as a minor product.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research