Syntheses of 1‐substituted 1,2,4‐triazoles, imidazoles and benzimidazoles | Zendy

Sharifian Abdollah | Zendy; Parang Kaykavoos | Zendy; ZorriehAmirian Hassan | Zendy; Nazarinia Mehrdad | Zendy; Shafiee Abbas | Zendy

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Syntheses of 1‐substituted 1,2,4‐triazoles, imidazoles and benzimidazoles

Author(s) -

Sharifian Abdollah,

Parang Kaykavoos,

ZorriehAmirian Hassan,

Nazarinia Mehrdad,

Shafiee Abbas

Publication year - 1994

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570310621

Subject(s) - chemistry , yield (engineering) , halide , hydride , sodium hydride , combinatorial chemistry , organic chemistry , medicinal chemistry , hydrogen , materials science , metallurgy

Substituted 2‐phenethyl‐1,2,4‐triazoles, 1‐phenethylimidazoles 3 and 1‐phenethylbenzimidazoles 5 were synthesized from the reaction of compound 8 with tri‐ n ‐butyltin hydride in good yield. The reaction of substituted‐2‐phenethyl halide with 1 H ‐1,2,4‐triazoles, imidazoles and benzimidazoles gave a low yield. The yield was increased by the use of substituted‐2‐phenethyl p ‐toluensulfonate.

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