3′‐Keto‐1‐nitro‐2‐phenylspiro[cyclopropane‐3,2′‐quinuclidine]: Synthesis and reactions with nucleophiles | Zendy

Besidsky Yevgeny | Zendy; Luthman Kristina | Zendy; Hacksell Uli | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

3′‐Keto‐1‐nitro‐2‐phenylspiro[cyclopropane‐3,2′‐quinuclidine]: Synthesis and reactions with nucleophiles

Author(s) -

Besidsky Yevgeny,

Luthman Kristina,

Hacksell Uli

Publication year - 1994

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570310604

Subject(s) - cyclopropane , chemistry , quinuclidine , nucleophile , nitro , ring (chemistry) , medicinal chemistry , trimethylsilyl cyanide , methoxide , lithium (medication) , stereochemistry , organic chemistry , methanol , catalysis , alkyl , medicine , endocrinology

3′‐Keto‐1‐nitro‐2‐phenylspiro[cyclopropane‐3,2′‐quinuclidine] was synthesized by a two‐step procedure from 2‐benzylidenequinuclidin‐3‐one. Ring‐opening reactions of the cyclopropane ring using a variety of N ‐, O ‐, and C ‐nucleophiles (amines, methoxide, nitromethanate, cyanide anions, and lithium diphenylcopper) were studied, and a general mechanism for the transformations is proposed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research