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Synthesis of 5,6‐dihydro‐4 H ‐pyrrolo[1,2‐ a ][1,4]benzodiazepine and 10,11‐dihydro‐5 H ,12 H ‐pyrrolo[2,1‐ c ][1,4]benzodiazocine derivatives via cyclization of 2‐aminomethylpyrroles
Author(s) -
Korakas D.,
Varvounis G.
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310603
Subject(s) - chemistry , benzodiazepine , stereochemistry , medicinal chemistry , biochemistry , receptor
We have synthesized pyrrolo[1,2‐α][1,4]benzodiazepine 6 and pyrrolo[2,1‐ c ][1,4]benzodiazocines 12 and 13 from the corresponding 1‐arylpyrrole 1d and 1‐benzylpyrroles 7a and 7b by routes involving four and five steps, respectively.