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Direct monobromination of substituted 4‐oxoquinoline‐3‐carboxylic acid derivatives
Author(s) -
Moẑek Irena,
Ŝket Boris
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310531
Subject(s) - chemistry , pyridinium , carboxylic acid , ethyl ester , fluoride , hydrogen fluoride , organic chemistry , medicinal chemistry , inorganic chemistry
N ‐Bromosaccharin in the presence of pyridinium poly(hydrogen fluoride) can be used for monobromination of ethyl esters of 6‐ and 7‐substituted‐4‐oxo‐1,4‐dihydroquinoline‐3‐carboxylic acids. The reactions take place at the C 6 or C 8 positions, depending on the types and positions of the substituents.
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