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The synthesis of azatryptophane derivatives
Author(s) -
Svete Jurij,
Stanovnik Branko,
Tiŝler Miha
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310524
Subject(s) - chemistry , optically active , amino acid , aspartic acid , stereochemistry , organic chemistry , biochemistry
Optically active and racemic isomers of aspartic acid ( 1 ) were transformed into the corresponding N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl esters ( 6 , R = Me) and N ‐trifluoroacetyl‐3‐formylalanine methyl esters 13 , which were used as starting compounds in the synthesis of β‐heteroaryl substituted‐α‐amino acids.
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