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Bridgehead nitrogen heterocycles derived from the potassium salt of 2,3,5,6,7,8‐hexahydro‐3‐amino‐2‐thioxo benzothieno[2,3‐ d ]pyrimidin‐4‐(1 H )‐one
Author(s) -
Santagati Andrea,
Modica Maria,
Santagati Maria
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310507
Subject(s) - chemistry , hydrazine (antidepressant) , salt (chemistry) , potassium , nitrogen , medicinal chemistry , organic chemistry , chromatography
Derivatives of tetraheterocyclic linear system 2, 4 and 5 were prepared by reacting the potassium salt 1 with the appropriate alpha ‐halocarbonyl compounds. Moreover, through reaction of methyl mercapto 6 with hydrazine the new heterocyclic system 1,4,7,8,9,10‐hexahydro‐6 H ‐[1]benzothieno[2′,3′:4,5]pyrimido[1,2‐ b ]‐[1,2,4,5]tetrazin‐6‐one ( 8 ) was also obtained.