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Reaction of 2‐trifluoromethyl‐4 H ‐3,1‐benzoxazin‐4‐one derivatives with carboethoxymethylenetriphenylphosphorane
Author(s) -
Murphy Steven M.,
Stanforth Stephen P.
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310465
Subject(s) - chemistry , trifluoromethyl , boiling , toluene , thermal decomposition , medicinal chemistry , organic chemistry , stereochemistry , alkyl
Treatment of a series of 2‐trifluoromethyl‐4 H ‐3,1‐benzoxazin‐4‐one derivatives 1 with carboethoxymethyl‐enetriphenylphosphorane 2 yielded the phosphoranes 3 in boiling toluene solution. Thermolysis of these phosphoranes 3 gave esters 6.