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Synthesis of 2 H ‐pyrano[2,3‐ b ]quinolines. Part I
Author(s) -
Cziáky Zoltán,
Sebők Péter
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310401
Subject(s) - chemistry , stereochemistry , cromakalim , medicinal chemistry , receptor , biochemistry , agonist
3,4‐Dihydro‐2 H ‐pyrano[2,3‐ b ]quinolines 5a‐e and 2 H ‐pyrano[2,3‐ b ]quinolines 10a‐c were synthesised starting from the appropriate ω‐chloro‐ n ‐valeroylanilides 2a‐e . Compounds 10a‐c were transformed to analogs of the novel antihypertensive agent Cromakalim ( 1 ).
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