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Synthesis and NMR characterization of 4‐[(2‐tetrahydro‐pyranyloxy)methyl]piperidine and intermediates
Author(s) -
Petric Andrej,
Barrio Jorge R.
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310249
Subject(s) - chemistry , piperidine , characterization (materials science) , organic chemistry , stereochemistry , nanotechnology , materials science
4‐(Hydroxymethyl)piperidine was selectively protected with tetrahydropyranyl group in several steps to give the title compound. Use of 1 H and 19 F nmr spectra in structure determination is discussed.