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Research on nitrogen and sulfur heterocyclic compounds: Synthesis of 10 H ‐pyrrolo[1,2‐ a ]thieno[3,4‐ e ][1,4]‐diazepin‐5(4 H )‐one and some derivatives
Author(s) -
Daich Abdelali,
Morel Jean,
Decroix Bernard
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310214
Subject(s) - chemistry , sulfur , intramolecular force , nitrogen , stereochemistry , medicinal chemistry , lactam , carboxylate , organic chemistry
The synthesis of 10 H ‐pyrrolo[1,2‐ a ]thieno[3,4‐ e ][1,4]diazepin‐5(4 H )‐one ( 16 ) and some derivatives are described from methyl 3‐bromomethylthiophene‐4‐carboxylate ( 5 ). The key step of these sequences is the intramolecular cyclization of the carbonylazides 12 and 13 .
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