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Synthesis of thieno[3,2‐ d ]pyrimidine‐2,4‐diones cyclic and acyclic nucleosides as potential anti HIV agents
Author(s) -
Jourdan Fabrice,
Ladurée Daniel,
Robba Max
Publication year - 1994
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570310208
Subject(s) - chemistry , pyrimidine , stereochemistry , combinatorial chemistry , human immunodeficiency virus (hiv) , virology , biology
Synthesis of cyclic and acyclic nucleosides was achieved by alkylation of 7‐methyl or arylthieno[3,2‐ d ]‐pyrimidine‐2,4‐diones following the Vorbrüggen and Niedballa's method [1]. After a possible deprotection, potential anti HIV agents were obtained.
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