Heterocyclizations in the pyrido[2,3‐ b ]pyrazine series | Zendy

Blache Y. | Zendy; Gueiffier A. | Zendy; Chavig O. | Zendy; Teulade J. C. | Zendy; Milhavet J. C. | Zendy; Viols H. | Zendy; Chapat J. P. | Zendy; Dauphin G. | Zendy

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Heterocyclizations in the pyrido[2,3‐ b ]pyrazine series

Author(s) -

Blache Y.,

Gueiffier A.,

Chavig O.,

Teulade J. C.,

Milhavet J. C.,

Viols H.,

Chapat J. P.,

Dauphin G.

Publication year - 1994

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570310127

Subject(s) - pyrazine , chemistry , indolizine , regioselectivity , series (stratigraphy) , reactivity (psychology) , stereochemistry , group (periodic table) , medicinal chemistry , organic chemistry , medicine , paleontology , alternative medicine , pathology , biology , catalysis

In this paper, we report the results of heterocyclizations in the pyrido[2,3‐ b ]pyrazine series to give the pyrido[2,3‐ e ] or [3,2‐ e ]pyrrolo[1,2‐ a ]pyrazine. The Clauson‐Kaas reaction on 2,3‐diaminopyridine is investigated; regioselectivity on the 3‐amino group is shown by 1 H‐ and 13 C‐nmr. Synthesis and reactivity of the original pyrazino[2,3‐ g ]indolizine series is also reported.

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