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A new approach for the synthesis of fused pyrroles. The synthesis of acyl substituted pyrrolo[1,2‐ x ]azines
Author(s) -
Čopar Anton,
Stanovnik Branko,
Tišler Miha
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300621
Subject(s) - chemistry , pyrazine , phenacyl , pyridine , pyrimidine , medicinal chemistry , pyridazine , stereochemistry
N ‐Acetonyl‐ and N ‐phenacyl quaternary salts of α‐methyl substituted heterocycles 16, 17, 21, 23 and 26 were converted with DMFDMA into the corresponding 3‐acylpyrrolo[1,2‐ a ]pyridine 18 , 7‐benzoylpyrrolo‐[1,2‐ c ]pyrimidine 22 , and 6‐benzoylpyrrolo[1,2‐ a ]pyrazine derivatives 24 and 27 . A concurrent reaction produced methyl and phenyl substituted pyrrolo[1,2‐ x ]azines 19, 20, 25 and 28 .