Synthesis of new 4‐quinolone‐type compounds in the benzo[ b ]thiophene series | Zendy

Février B. | Zendy; Dupas G. | Zendy; Bourguig J. | Zendy; Quéguiner G. | Zendy

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Synthesis of new 4‐quinolone‐type compounds in the benzo[ b ]thiophene series

Author(s) -

Février B.,

Dupas G.,

Bourguig J.,

Quéguiner G.

Publication year - 1993

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570300442

Subject(s) - chemistry , thiophene , pyridine , quinolone , ring (chemistry) , amine gas treating , stereochemistry , series (stratigraphy) , combinatorial chemistry , medicinal chemistry , organic chemistry , antibiotics , biochemistry , paleontology , biology

Some new derivatives of 1,4‐dihydro‐4‐oxo‐3‐pyridinecarboxylic acid (quinolone‐type compounds) 5 and 13 have been prepared in the benzo[ b ]thiophene series. The key step was the construction of the pyridine ring starting from 2‐aminobenzo[ b ]thiophene derivatives. The synthesis of amine 9 , was performed by using an original “animation” reaction.

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