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On the reaction between 3 H ‐1,2‐dithiolo[3,4‐ b ]pyridine‐3‐thione and primary alkyl and arylalkylamines
Author(s) -
Borgna Pietro,
Pregnolato Massimo,
Invernizzi Anna Gamba,
Mellerio Giorgio
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300441
Subject(s) - chemistry , pyridine , yield (engineering) , medicinal chemistry , primary (astronomy) , alkyl , stereochemistry , organic chemistry , materials science , physics , astronomy , metallurgy
3 H ‐1,2‐Dithiolo[3,4‐ b ]pyridine‐3‐thione ( 10 ) reacts with primary alkylamines to give 1,2‐dihydro‐2‐thioxo‐3‐pyridinecarbothioamides 11a‐g and two minor products. Isothiazolo[5,4‐ b ]pyridine‐3(2 H )‐thiones 12a‐g and 3‐imino‐3 H ‐1,2‐dithiolo[3,4‐ b ]pyridines 13a‐g were isolated and characterized. Further investigations allowed the synthesis of 12 and 13 in good yield.