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Synthesis of 5‐phenyl‐2,3,8,9‐tetramethoxy‐11 H ‐indeno[1,2‐ c ]isoquinoline
Author(s) -
Ibañez Adriana F.,
Martinez Andrea R.,
Iglesias Graciela Y. Moltrasio
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300435
Subject(s) - chemistry , isoquinoline , friedel–crafts reaction , cinnamic acid , amide , organic chemistry , medicinal chemistry , catalysis
A novel approach to the title compound 10 starting with a conveniently available cinnamic acid is proposed. It involves a Friedel‐Crafts reaction followed by the synthesis of the amide and subsequent cyclodehydration via a Bischler‐Napieralski reaction.