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A novel practical synthesis of pyrrolo[1,2‐ a ]thieno[2,3‐ e ][1,4]diazepines
Author(s) -
Daich Abdelali,
Morel Jean,
Decroix Bernard
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300317
Subject(s) - diazepine , ring (chemistry) , d 1 , closure (psychology) , combinatorial chemistry , chemistry , stereochemistry , organic chemistry , political science , law , biochemistry , receptor
In an investigation of new heterocyclic systems, a novel way to obtain pyrrolo[1,2‐ a ]thieno[2,3‐ e ][1,4]diazepine 8 was effected by ring closure to the appropriate nitroaldehyde compound which was synthesized in five steps from 3‐bromomethyl‐2‐nitrothiophene 1 .