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The reaction of pyrroles with trimethylhalosilanes‐dialkyl sulfoxides
Author(s) -
Bellesia Franco,
Ghelfi Franco,
Grandi Romano,
Pagi Ugo Maria,
Pinetti Adriano
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300306
Subject(s) - chemistry , organic chemistry , combinatorial chemistry , medicinal chemistry
Pyrroles are powerful nucleophiles in the reaction with dialkyl sulfoxides and trimethylchlorosilane (TMCS) or trimethylbromosilane (TMBS), affording sulfonium salts or halo derivatives, generally in good yields.