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A new method for the synthesis of 6 H ,11 H ‐indolo[3,2‐ c ]‐isoquinolin‐5‐ones/thiones and their reactions
Author(s) -
Hiremath Shivayogi P.,
Saundane Ananda R.,
Mruthyunjayaswamy B. H. M.
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300304
Subject(s) - chemistry , stereochemistry , medicinal chemistry
The synthesis of 8‐substituted and unsubstituted 6 H ,11 H ‐indolo[3,2‐ c ]isoquinolin‐5‐ones/thiones 3a‐c and 4a‐c and their derivatives viz , ethyl (8‐substituted‐6 H ,11 H ‐indolo[3,2‐ c ]isoquinolin‐5‐on‐6‐yl)acetates 5a‐c , (8‐substituted‐6 H ,11 H ‐indolo[3,2‐ c ]isoquinolin‐5‐on‐6‐yl)acetyl hydrazides 6a‐c , 3,5‐disubstituted‐pyrazoles 7a‐c and 8a‐c , 3‐substituted‐pyrazol‐5‐ones 9a‐c and 5‐(8‐substituted‐6 H ,11 H ‐indolo[3,2‐ c ]isoquinolin‐5‐on‐6‐yl)methyl‐1,3,4‐oxadiazole‐2‐thiones 10a‐c , also ethyl (8‐substituted‐11 H ‐indolo[3,2‐ c ]isoquinolin‐5‐ylthio)ace‐tates 11a‐c , (8‐substituted‐11 H indolo[3,2‐ c ]isoquinolin‐5‐ylthio)acetyl hydrazides 12a‐c , 3,5‐disubstituted‐pyrazoles 13a‐c and 14a‐c , 3‐substituted‐pyrazol‐5‐ones 15a‐c and 5‐(8‐substituted‐11 H ‐indolo[3,2‐ c ]isoquin‐olin‐5‐yl)thiomethyl‐1,3,4‐oxadiazole‐2‐thiones 16a‐c is described.