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Preparation of some substituted imidazo[1,2‐ a ]pyridine derivatives
Author(s) -
Shawcross Andrew P.,
Stanforth Stephen P.
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300253
Subject(s) - chemistry , pyridine , aminopyridines , ammonia , medicinal chemistry , organic chemistry , combinatorial chemistry
2‐Bromopyridine derivatives 2a‐2c were prepared. Compounds 2b and 2c and ammonia yielded aminopyridines 3b and 3c which were converted to imidazo[1,2‐ a ]pyridine derivatives 4b and 4c . Compound 4b was nitrated giving the analogue 5b of metronidazole 1 .
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