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One step synthesis of dihydropyrrolo[3,2‐ e ]indoles from 1,4‐cyclohexanedione
Author(s) -
Lash Timothy D.,
Bellettini John R.,
Voiles Steven J.
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300242
Subject(s) - chemistry , condensation , acetic acid , sodium acetate , zinc , organic chemistry , sodium , one step , physics , thermodynamics , art , visual arts
Condensation of phenylhydrazones 1a‐c with 1,4‐cyclohexanedione in the presence of zinc dust, sodium acetate and acetic acid gave the 4,5‐dihydropyrrolo[3,2‐ e ]indoles 7a‐c. Oxidation of 7a with DDQ afforded the fully aromatic pyrroloindole 16.
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