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The structure of new cis and trans 3′‐phenyl‐3′,3a′,4′,5′,6′,7a′‐hexahydro‐2,1‐benzisoxazole‐7a′‐spiro‐2‐(3‐phenylaziridine)
Author(s) -
Diaz Eduardo,
Barrios Héctor,
Yuste Francisco,
Aguilera José Luis,
Reynolds William F.,
Van Calsteren Marie Rose,
Jankowski Christopher
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300117
Subject(s) - chemistry , aziridine , hydroxylamine hydrochloride , hydroxylamine , cis–trans isomerism , stereochemistry , hydrochloride , crystal structure , ring (chemistry) , medicinal chemistry , crystallography , organic chemistry
The reaction of dibenzalcyclohexanone with hydroxylamine hydrochloride afforded three compounds 1–3 including the aziridine 3 showing a 3′,3a′‐ trans configuration. Now we report on the isolation of a new aziridine 4 , possessing a 3′,3a′‐ cis configuration. Its structure was deduced by 2D nmr and single crystal X‐ray diffraction studies.