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Structural study of 3‐methyl‐2,4‐diphenyl‐3‐azabicyclo[3.3.1]nonan‐9β‐ol
Author(s) -
Iriepa I.,
GilAlberdi B.,
Galvez E.,
Torres R.,
GomezSal P.,
Bellanato J.
Publication year - 1993
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570300105
Subject(s) - chemistry , ring (chemistry) , piperidine , bicyclic molecule , cyclohexane conformation , cyclohexane , stereochemistry , crystal structure , methyl group , group (periodic table) , crystallography , medicinal chemistry , molecule , organic chemistry , hydrogen bond
The infrared spectra in several media and the crystal structure of 3‐methyl‐2,4‐diphenyl‐3‐azabicyclo[3.3.1]‐nonan‐9β‐ol ( I ) (Scheme I) have been determined, in order to complete the structural study described for the title compound from the 1 H and 13 C nmr data [1]. The bicyclic system adopts a flattened chair‐chair conformation in which the cyclohexane ring is more flattened. The methyl and phenyl groups are in equatorial positions and the OH group in an axial position with respect to the piperidine ring.