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On the synthesis and reactivity of 4,10‐dihydrobenzo‐[ b ]thieno[2,3‐ e ]thiepin‐10‐acetic acid and 5,10‐dihydrobenzo[ e ]thieno[3,2‐ b ]thiepin‐10‐acetic acid
Author(s) -
Daich A.,
Decroix B.
Publication year - 1992
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570290720
Subject(s) - chemistry , acetic acid , reactivity (psychology) , medicinal chemistry , organic chemistry , medicine , alternative medicine , pathology
A simple method to synthesize 4,10‐dihydrobenzo[ b ]thieno[2,3‐ e ]thiepin‐10‐acetic acid (8a) and 5,10‐dihydrobenzo[ e ]thieno[3,2‐ b ]thiepin‐10‐acetic acid (8b) starting from ketones la,b is described. The reactivity of the acid 8a has been investigated and some derivatives are reported.